Po praznovanju 20. obletnice delovanja, so se Dream Theater odločili, da bodo izdali že drugi best-of, ki ga bodo naslovili “Greatest Hit (…& 21 Other Pretty Songs)”, izšel pa bo 01. aprila pri založbi Rhino. Best- of bo vseboval dva ploščka, ki bosta zajemala obdobe od 1991 di 2005.
Tracklista:
Disc 1 (The Dark Side):
01. Pull Me Under (2007 Remix)
02. Take The Time (2007 Remix)
03. Lie (Single Edit)
04. Peruvian Skies
05. Home (Single Edit)
06. Misunderstood (Single Edit)
07. The Test That Stumped Them All
08. As I Am
09. Endless Sacrifice
10. The Root Of All Evil
11. Sacrificed Sons
Disc 2 (The Light Side):
01. Another Day (2007 Remix)
02. To Live Forever
03. Lifting Shadows Off A Dream
04. The Silent Man
05. Hollow Years
06. Through Her Eyes (Alternate Album Mix)
07. The Spirit Carries On
08. Solitary Shell (Single Edit)
09. I Walk Beside You
10. The Answer Lies Within
11. Disappear
